UHLIROVA LAB

Floc'hlay S, Balaji R, Stankovic D, Christiaens VM, Bravo Gonzalez-Blas C, De Winter S, Hulselmans GJ, De Waegeneer M, Quan X, Koldere D, Atkins M, Halder G, Uhlirova M, Classen A & Aerts S. (2023) Shared enhancer gene regulatory networks between wound and oncogenic programs, Elife. 12, e81173, DOI: 10.7554/eLife.81173.

Stankovic D, Csordás G, Uhlirova M. (2023) Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes, Life Sci Alliance. 6, e202201801, DOI: 10.26508/lsa.202201801

Külshammer E, Kilinc M, Csordás G, Bresser T, Nolte H, Uhlirova M. (2022) The mechanosensor Filamin A/Cheerio promotes tumorigenesis via specific interactions with components of the cell cortex. The FEBS Journal, 289, 4497–4517,  DOI: 10.1111/febs.16408

Erkelenz S, Stankovic D, Mundorf J, Bresser T, Claudius A-K, Boehm V, Gehring NH, Uhlirova M. (2021) Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Research, 49, 1688-1707, DOI: 10.1093/nar/gkaa1274

Csordás G, Grawe F, Uhlirova M. (2020) Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments. eLife 9, DOI: 10.7554/eLife.57297

Stankovic D, Claudius A, Schertel T, Bresser T, Uhlirova M. (2020) A Drosophila model to study retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8. Disease Models & Mechanisms, 13: dmm043174. DOI: 10.1242/dmm.043174. Article in PubMed

Mundorf J, Donohoe CD, McClure CD, Southall TD, Uhlirova M. (2019) Ets21c governs tissue renewal, stress tolerance, and aging in the Drosophila intestine. Cell Reports, 27: 3019-3033. DOI: 10.1016/j.celrep.2019.05.025. Article in PubMed

Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen A. (2019) JNK-dependent cell 1 cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. eLife, 8: e41036. DOI: 10.7554/eLife.41036. Article in PubMed

Donohoe CD, Csordás G, Correia A, Jindra M, Klein C, Habermann B, Uhlirova M. (2018) Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture. PLoS Genetics, 14: e1007241. Article in PubMed

Martinez Carrera LA, Gabriel E, Donohoe CD, Hölker I, Mariappan A, Storbeck M, Uhlirova M, Gopalakrishnan J, Wirth B. (2018) Novel insights into SMALED2: BICD2 mutations increase microtubule stability and cause defects in axonal and NMJ development. Human Molecular Genetics, 10: 1772-1784. Article in PubMed

Mundorf J and Uhlirova M. (2016) The Drosophila imaginal disc tumor model: visualization and quantification of gene expression and tumor invasiveness using genetic mosaics. J. Vis. Exp., 116: e54585. Article in PubMed

Külshammer E, Mundorf J, Kilinc M, Frommolt P, Wagle P, Uhlirova M. (2015) Interplay among transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy. Disease Models & Mechanisms, 8: 1279-1293. Article in PubMed

Jindra M, Uhlirova M, Charles JP, Smykal V, Hill RJ. (2015) Genetic Evidence for Function of the bHLH-PAS Protein Gce/Met as a Juvenile Hormone Receptor. PLoS Genetics, 11: e1005394. Article in PubMed

Claudius A, Romani P, Lamkemeyer, T, Jindra M, Uhlirova M. (2014) Unexpected Role of the Steroid-Deficiency Protein Ecdysoneless in Pre-mRNA Splicing. PLoS Genetics, 1: e1004287. Article in PubMed

Külshammer E and Uhlirova M. (2013) The actin cross-linker Filamin/Cheerio mediates tumor malignancy downstream of JNK signaling. Journal of Cell Science, 126: 927–938. Article in PubMed

Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M. (2012). Activating transcription factor 3 regulates immune and metabolic homeostasis. Molecular and Cellular Biology, 32: 3949-62. Article in PubMed

Sekyrova P, Bohmann D, Jindra M, Uhlirova M. (2010) Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development, 137: 141-150. Article in PubMed

Wang Q, Uhlirova M, Bohmann D. (2010) Spatial Restriction of FGF Signaling by a Matrix Metalloprotease Controls Branching Morphogenesis. Developmental Cell, 18: 157-164. Article in PubMed

Uhlirova M and Bohmann D. (2006) JNK and Fos regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J., 25: 5294-5304. Article in PubMed

Uhlirova M, Jasper H, Bohmann D. (2005) Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model. Proc. Natl. Acad. Sci. USA 102: 13123-13128. Article in PubMed

Jindra M, Gaziova I, Uhlirova M, Okabe M, Hiromi Y, Hirose S. (2004) Coactivator MBF1 preserves the redox-dependent AP-1 activity and its loss causes sensitivity to oxidative stress in Drosophila. EMBO J., 23: 3538-3547. Article in PubMed

Foy BD, Myles KM, Pierro DJ, Sanchez-Vargas I, Uhlirova M, Jindra M, Olson KE. (2004) Development of a new Sindbis virus transducing system and its characterization in three Culicine mosquitoes and two Lepidopterans. Insect Molecular Biology, 13: 89-100. Article in PubMed

Jindra M and Uhlirova M. (2004) Use of piggyBac and a Sindbis Virus for Foreign Gene Expression and RNAi in the Silkworm. In: Transgenic Silkworms(ed. K. Yoshizato), Landes Bioscience.

Uhlirova M, Foy BD, Riddiford LM, Beaty BJ, Olson KE, Jindra M. (2003) Use of Sindbis virus-mediated RNA interference to demonstrate a conserved role of Broad-Complex in insect metamorphosis. Proc. Natl. Acad. Sci. USA, 100: 15607-15612. Article in PubMed

Uhlirova M, Asahina M, Riddiford LM, Jindra M. (2002) Heat inducible transgenic expression in the silkmoth Bombyx mori. Development Genes & Evolution, 212: 145-151. Article in PubMed

Kucerova D, Sloncova E, Tuhackova Z, Uhlirova M, Kos M, Sovova V. (1999) Changes of E-cadherin and beta-catenin levels during induced differentiation of colorectal carcinoma cells. International Journal of Molecular Medicine, 4: 541-544. Article in PubMed